This medicinal product is for diagnostic use only. After radiolabeling with sodium (99mTc)-pertechnetate solution, the solution obtained is indicated in adults and children for bone scintigraphy for the detection of areas of altered
osteogenesis associated with Neoplasms and Non-neoplastic lesions.

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The availability of technetium-based bone-seeking pharmaceuticals with improved soft-tissue clearance has led to sensitive, high-resolution images.

The skeleton is a complex system that performs several functions for the body including support, protection, movement, and blood formation via the blood marrow in some of the skeleton.

Radionuclide imaging of the skeleton is useful in the evaluation of osteoblastic abnormalities or altered osteogenesis involving bone and joints. This bone scintigraphy often provides an earlier, more sensitive diagnosis and often demonstrates more lesions than are found by common plain film radiographic procedures (metastatic disease, early osteomyelitis and avascular necrosis, stress fractures, occult fractures). Although the presence of a lesion on a bone scintigraphy can be non-specific in the absence of clinical information, its excellent sensitivity often provides important early recognition and direction for a complete differential diagnosis.

The addition of a clinical history, clinical correlation or complementary studies adds considerably specificity that allows a more definitive evaluation and diagnosis.

Product overview

Product name

Kit for the Preparation of Technetium Tc 99m Medronate Injection


MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis.


None known at present


Each kit consists of reaction vials which contain the sterile, non-pyrogenic, non-radioactive ingredients necessary to produce Technetium Tc 99m Medronate Injection for diagnostic use by intravenous injection. Available in kits containing 30 reaction vials.


  • MDP-25 reaction vials are intended to be used as multidose vials.
  • Care should be taken to ensure that each reconstituted dose of
    99mTc-MDP-25 contains between 1 and 10 mg of medronic acid. Refer to the Product Insert for the detailed calculations.

Specific Product Characteristics

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Safety Data Sheet

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This information is not intended as medical advice. Responsibility for patient care resides with the healthcare professional on the basis of his or her professional license, experience and knowledge of the patient. For full Prescribing Information including indications, contraindications, warnings, precautions and adverse events, please see the appropriate product labeling.