RUBY-FILL® (Rubidium Rb82 Generator)

RUBY-FILL® (Rubidium Rb82 Generator)The RUBY-FILL® Rubidium 82 Generator contains an accelerator produced Strontium-82, which decays to Rubidium-82. When the generator is eluted with saline it produces a sterile, non-pyrogenic solution of Rb-82 Chloride.

Due to the short half-life (75 s) of Rb-82, the use of an elution system is required for delivery of the Rb-82 Chloride into a patient for the purposes of performing Myocardial Perfusion Imaging with PET.  PET imaging with Rb-82 Chloride may be performed under rest and/or stress conditions.

The Rubidium Elution System has been exclusively designed to be used with the RUBY-FILL® generator and to deliver accurate doses of Rb-82 Chloride to patients.

For more information, please contact: Medical & Regulatory Affairs

or visit

Important Safety Information


Please see full prescribing information for complete boxed warning

  • Unintended radiation exposure occurs when the levels of Sr 82 or Sr 85 in the rubidium Rb 82 chloride injection exceed specific limits.
  • Perform generator eluate tests:

1) Determine Rb 82, Sr 82, Sr 85 levels in the eluate:

  •  Once daily, prior to any drug administration, and
  •  With additional daily tests after detection of an Alert Limit.

2) Stop use of the generator at its Expiration Limit.

Click here to view full prescribing information


This information is not intended as medical advice. Responsibility for patient care resides with the healthcare professional on the basis of his or her professional license, experience and knowledge of the patient. For full Prescribing Information including indications, contraindications, warnings, precautions and adverse events, please see the appropriate product labeling.