Jubilant DraxImage is dedicated to providing radiopharmaceuticals for the diagnosis and treatment of a variety of diseases. We invite you to learn more about these areas and how our products are used by healthcare professionals to care for their patients.
The blood-brain barrier (BBB) refers to the anatomic and physiologic membrane between circulating blood and the brain preventing certain damaging substances from reaching brain tissue and cerebrospinal fluid. This barrier permits nutrients essential to brain tissue to readily cross the barrier while toxic and unwanted substances are restricted from passage. DRAXIMAGE® Gluceptate, although non-toxic, cannot penetrate the blood-brain barrier unless there is a breakdown in the BBB as a result of disease.
Radionuclide imaging studies of the kidneys are sensitive indexes of relative renal blood flow, tubular function and urinary excretion. Specific radionuclides are used as their mode of excretion isolates certain elements of renal function. 99mTc-Gluceptate can be used for renal perfusion and sequential imaging.
The multiple equilibrium-gated-radionuclide ventriculogram is a non-invasive, widely available method to examine the function of the pumping chambers of the heart. Ventricular size, configuration, and wall-motion information complement measurements of the ejection fraction.
Kit for the Preparation of Technetium Tc 99m Gluceptate Injection or Stannous Gluceptate Injection
The kit consists of reaction vials which contain the sterile, non-pyrogenic, non-radioactive ingredients necessary to produce either Technetium Tc 99m Gluceptate Injection for diagnostic use in kidney and brain imaging or Stannous Gluceptate Injection for diagnostic use in cardiac blood pool imaging. Both diagnostic products are administered by intravenous injection. Available in kits containing 5 reaction vials.
Technetium Tc 99m Gluceptate Injection for Brain and Kidney Imaging
The addition of Sodium Pertechnetate Tc 99m Injection to produce Technetium Tc 99m Gluceptate Injection results in the rapid labeling of calcium gluceptate which is essentially quantitative and which remains stable throughout the useful life of the preparation.Stannous Gluceptate Injection for Cardiac Blood Pool Imaging
The contents of the kit may be reconstituted with sterile, non-pyrogenic preservative-free normal saline to form Stannous Gluceptate Injection for cardiac blood pool imaging and administered 10 to 30 minutes before injecting Sodium Pertechnetate Tc 99m Injection.
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This information is not intended as medical advice. Responsibility for patient care resides with the healthcare professional on the basis of his or her professional license, experience and knowledge of the patient. For full Prescribing Information including indications, contraindications, warnings, precautions and adverse events, please see the appropriate product labeling.